Laudanum is still around for end stage terminal cancer pain. It still works the best. It is usually a part of Brompton’s Solution. Opium dissolved in Vodka with some Cocaine and flavor added. Enough analgesia to numb the pain, enough Cocaine to keep you awake and breathing. Nobody ever takes this stuff for long.
One of the hospitals I trained in 45 years ago was over 70 years old then. In their museum they had an empty bottle of Heroin Throat Spray for use with children with Strep. throat.
Morphine and Opium addiction was also a big problem just after the Civil War. Many disabled Veterans used it because of old war wounds and phantom pain from amputated legs and arms. One thing that really caused a big problem was the new Glass Syringe and hollow Hypodermic Needle. Injected opioids great addiction faster than by mouth.
It was one of the few drugs available. Phenobarbital (a very old minor tranquilizer and epilepsy drug was synthesized in the 1890s, but didn’t catch on in the States until later.Paraldehyde was also available 100 years ago, but the smell and taste would gag a buzzard.
Hey, look, if I’m in pain I want my mu-receptors, my sigma-receptors, my zeta-receptors, and my kappa-receptors flooded. I mean all of them activated and extra opioids swirling around in case some got lost in the first pass.Nausea? Give me some ProchlorperazineRespiratory Arrest? Bag me, and titrate Naloxone until I can breathe on my own. But not enough to wake me up.
Trix came close!
(Okay, fine, not an overdose per se.)
Neat, I hadn't heard of that one before!
Laudanum is still around for end stage terminal cancer pain. It still works the best. It is usually a part of Brompton’s Solution. Opium dissolved in Vodka with some Cocaine and flavor added. Enough analgesia to numb the pain, enough Cocaine to keep you awake and breathing. Nobody ever takes this stuff for long.
One of the hospitals I trained in 45 years ago was over 70 years old then. In their museum they had an empty bottle of Heroin Throat Spray for use with children with Strep. throat.
Now China sends us most of our bootleg Fentanyl.
Morphine and Opium addiction was also a big problem just after the Civil War. Many disabled Veterans used it because of old war wounds and phantom pain from amputated legs and arms. One thing that really caused a big problem was the new Glass Syringe and hollow Hypodermic Needle. Injected opioids great addiction faster than by mouth.
It was one of the few drugs available. Phenobarbital (a very old minor tranquilizer and epilepsy drug was synthesized in the 1890s, but didn’t catch on in the States until later.Paraldehyde was also available 100 years ago, but the smell and taste would gag a buzzard.
There was a Little House on the Prairie episode about that very issue! (😁)
How about the death penalty for Purdue Pharma. After all "Corporations are people my friend."
Hey, look, if I’m in pain I want my mu-receptors, my sigma-receptors, my zeta-receptors, and my kappa-receptors flooded. I mean all of them activated and extra opioids swirling around in case some got lost in the first pass.Nausea? Give me some ProchlorperazineRespiratory Arrest? Bag me, and titrate Naloxone until I can breathe on my own. But not enough to wake me up.
The crisis has also severely impacted communities of color, exacerbated by existing health disparities.
So, working well.
Here's the truth: fueling addiction is big business.
You lost me at "Here's the truth."
Here, I've got a few extra: ,,,,,,,,,,,,, ,,,,
She had a neurological disorder called essential tremor.
Not to him, but some idiots it does.
Can we please get all the “B” guys off the news and talk about issues for cripes sake?!?
So does this count as a cletus safari?
Also: I happen to think those "This is your brain on drugs" ads were the best thing ever.